WebJun 1, 2003 · Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. More active towards saturated and unsaturated long chain fatty acyl-CoAs (C12-C20). 1 publication Catalytic activity H2O + hexadecanoyl-CoA = CoA + H+ + hexadecanoate 1 publication WebJan 27, 2024 · Fatty acyl-ACP thioesterases determine the length of the fatty acid carbon chains through releasing acyl chain from acyl-ACP. ... cells and Arabidopsis fatb mutant plants showed that the presence of VfFATB led to accumulation of 18:0 and 18:3 fatty acids in vivo. In vitro thioesterase assay using crude extract from seed tissue of tung tree and ...
Acyl-CoA thioesterase-2 facilitates mitochondrial fatty acid …
WebJun 19, 2007 · Acyl-CoA thioesterases (Acots) catalyze the hydrolysis of fatty acyl-CoA to free fatty acid and CoA and thereby regulate lipid metabolism and cellular signaling. We present a comprehensive structural and functional characterization of mouse acyl-CoA thioesterase 7 (Acot7). ... These results are supported by an increase in acyl-CoA … WebJan 3, 2013 · Fatty acids (FAs) are activated to CoA esters extraperoxisomally by as-yet unidentified acyl-CoA synthetases. The ABC transporter, CTS, binds fatty acyl-CoAs on … cronobike
Thioesterase enzyme families: Functions, structures, and …
WebJan 23, 2007 · a fatty acyl-CoA + H2O = a fatty acid + CoA + H+ 6 publications This reaction proceeds in the forward direction. Curated EC:3.1.2.20 ( UniProtKB ENZYME Rhea) Source: Rhea 16781 Hide Rhea reaction a fatty acyl-CoA CHEBI:77636 zoom + H 2 O CHEBI:15377 zoom = a fatty acid CHEBI:28868 zoom + CoA CHEBI:57287 zoom + H … WebOct 9, 2024 · Acyl-ACP thioesterase (TE) catalyzes the hydrolysis of thioester bonds during type II fatty acid synthesis and directly determines fatty acid chain length. Most TEs are responsible for... WebAug 20, 2024 · Certain fatty acids stabilize the START domain and allosterically enhance Them1 catalysis of acyl-CoA, whereas 18:1 LPC destabilizes and inhibits activity, which we verify in cell culture. Additionally, we demonstrate that the START domain functions to localize Them1 near lipid droplets. cronobacter sakazakii uti