WebJan 10, 2024 · A considerable number of known molecular factors are involved in the regulation of GC apoptosis, including proapoptotic molecules, such as FAS (Fas cell … WebNational Center for Biotechnology Information
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WebJun 15, 2024 · The exclusive criteria of PCOS women; 1, diagnosed with hyperprolactinemia; 2, abnormal androgen secretion due to adrenal or ovarian tumors; 3, patients with uncorrected thyroid disease; 4, suspected Cushing’s syndrome; 5, using estrogen or oral contraceptives and other hormone drugs in recent one month; 6, using other drugs that … WebJan 1, 2024 · A Foxl2 promoter-driven knockout of Yap1 in ovarian granulosa cells resulted in increased apoptosis of granulosa cells, decreased the number of corpora lutea, reduced ovarian size, and resulted in subfertility of transgenic mice 40. The relationship between miR-484 and YAP1 has been previously reported.
WebJan 10, 2024 · The regulation of ovarian granulosa cell death by pro-and anti-apoptotic molecules. J Reprod Dev. 2006;52:695–705. Article CAS PubMed Google Scholar Manabe N, Kimura Y, Uchio K, Tajima C, Matsushita H, Nakayama M, Sugimoto M, Miyamoto H. Regulatory mechanisms of granulosa cell apoptosis in ovarian follicle atresia. WebJul 26, 2024 · Primary rat ovarian granulosa cells (OGCs) were collected from ovarian tissues and identified by cell immunohistochemistry. The effects of miR-126-3p-hucMSCs-exosomes and miR-126-3p on OGCs function were determined by cell proliferation and apoptosis assays in a cisplatin induced POF cell model.
WebApr 11, 2024 · This may be because full-term PPE promotes the proliferation of pre-granulosa cells, while mid-late pregnancy exposure inhibits apoptosis of pre-granulosa cells, thus affecting the expression of CYP19 in fetal ovarian pre-granulosa cells. However, the specific mechanism needs to be further explored. WebOct 26, 2024 · Polycystic ovary syndrome (PCOS) is one of the most incident reproductive endocrine diseases, with a prevalence ranging from 5 to 10% in women of reproductive …
WebNov 20, 2024 · Journal of Ovarian Research 13, Article number: 135 ( 2024 ) Cite this article 1809 Accesses 4 Citations Metrics Abstract Background In mammals, it is known that the estradiol-17β (E2) is mainly synthetized in ovarian granulosa cells (GCs), and the excessive apoptosis of GCs induces the follicular atresia.
WebThe main characteristic of follicle atresia is the apoptosis of oocytes, granulosa cells and theca cells. ... Tang X, Ma L, Guo S, Liang M, Jiang Z. High doses of FSH induce autophagy in bovine ovarian granulosa cells via the AKT/mTOR pathway. Reprod Domest Anim. 2024; 56:324–32. [Google Scholar] 21. cem in hill nhWebAfter the adoptive transfer of Treg cells overexpressing Peli1 in autoimmune POI mice, the apoptosis rate of ovarian granulosa cells declined. The levels of the inflammatory inhibitors interleukin 10 and transforming growth factor-β as well as the ovarian hormone estradiol were elevated. The number of primordial, primary, secondary, and mature ... buy highlighter makeupWebJun 1, 2024 · The apoptosis rate of the cisplatin-induced group was significantly higher than that of the control group, indicating that the establishment of ovarian granulosa cell … buy highlighter makeup online indiaWebFeb 27, 2024 · This phenomenon induces significant apoptosis of granulosa cells, which is the cellular basis of ovarian follicular atresia [ 86, 87 ], as it leads to reduced levels of sex hormones secreted by non-resting follicular granulosa cells [ 88 ]. In addition to apoptosis, inhibition of autophagy has been shown to be involved in follicular loss. buy highland park whisky duty freeWebJun 1, 2024 · Human ovarian granulosa cell line (KGN cell) was obtained from Prof. Jiangning Zhou as a gift. In previous studies, KGN cell line was considered as a very useful model that mimicked the physiological regulation of steroidogenesis, cell growth, and apoptosis in human granulosa cells [29, 30]. buy highly modified carsWebApr 5, 2024 · The regulation of granulosa cells (GCs) proliferation and apoptosis is the key step in follicular selection which determines the egg production performance of poultry. miR-202-5p has been reported to be involved in regulating the proliferation and apoptosis of mammalian ovarian GCs. However, its role in regulating the proliferation and ... buy highlights hidden pictures magazineWebNov 23, 2007 · Granulosa cell culture. Ovaries were obtained from cows and heifers at a local abattoir. Granulosa cells from small follicles (under 5 mm) were collected by aspiration and filtrated through a stainless steel filter (45 μm, Tokyo Screen Co., Ltd., Tokyo, Japan) to remove oocytes. buy high low wedding dress uk