Web13. dec 2024 · TOPGEAR, led by Prof Trevor Leong, is a randomised trials investigating neoadjuvant strategies for gastric cancer. “The trial is in the final stages of recruitment and with over 500 patients recruited, it is already the largest trial evaluating preoperative chemoradiation for gastric cancer,” says Prof Leong. Web13. apr 2024 · The population in the case group signed an informed consent form, aged between 18 and 75 years. All subjects underwent endoscopic examination and were confirmed by pathological diagnosis as gastric cancer, including high-grade intraepithelial neoplasia, early gastric cancer, and advanced gastric cancer. Control:
ASCO 2024–Gastroesophageal tumor highlights SpringerLink
Web30. apr 2024 · The landmark trial that has established nCTRT as the standard practice for the treatment of resectable esophageal cancer is the Chemoradiotherapy for Oesophageal Cancer Followed by Surgery Study (CROSS) trial.22Patients with both SCC and AC of T1N1M0 or T1-3N0-1M0were randomized to nCTRT (n = 178) and to surgery (n = 188) … Web13. apr 2024 · The FDA has set a Prescription Drug User Fee Act date of December 16, 2024 for this indication. Supporting data for this application come from come from the phase 3 KEYNOTE-859 trial (NCT03675737), in which the addition of pembrolizumab to chemotherapy yielded a statistically significantly improved overall survival (OS) regardless … plenty cereal
TOPGEAR results set to unify global treatment of gastric cancer
Web16. feb 2024 · Gastric cancers from Eastern countries, such as Japan and Korea, have lower proportions with signet ring histology and proximal stomach involvement. 3-6 Because of the lower proportion of cases with these adverse factors, most large, randomized trials from the East demonstrate survival rates that are 30% to 40% higher than trials from the West ... Web21. júl 2015 · TOPGEAR: a randomised phase III trial of perioperative ECF chemotherapy versus preoperative chemoradiation plus perioperative ECF chemotherapy for resectable … plenty cea