WebJun 1, 2024 · Long noncoding RNA (lncRNA) is a type of non-coding RNA that is at least 200 nucleotides in length and does not encode any protein (Zhang et al. 2024 ). In recent years, lncRNA has been found to have the function of trapping microRNA (miRNA) and regulating gene functions by reducing the expression level of some miRNAs (Guo et al. … WebThe lncRNA taurine-upregulated gene 1 (TUG1) directly binds to polycomb repressive complex 2 (PRC2) or PRC1 represses gene expression, and has been reported to …
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WebJan 29, 2024 · LncRNA TUG1 reduces inflammation and enhances insulin sensitivity in white adipose tissue by regulating miR-204/SIRT1 axis in obesity mice. LncRNA TUG1 competitively binds to miR-340 to accelerate myocardial ischemia-reperfusion injury. The Tug1 lncRNA locus is essential for male fertility. WebThe lncRNA TUG1, short for Taurine upregulated gene 1, was originally reported to be upregulated in response to taurine treatment of developing mouse retinal cells and has been frequently described as an oncogene in various human cancers. 34–36 UCA1 (urothelial carcinoma associated 1) was initially identified in human bladder carcinoma and ... bothy kits uk
The lncRNA TUG1 promotes epithelial ovarian cancer cell …
WebPrevious studies indicated lncRNA TUG1 was upregulated in bladder cancer, gastric cancer, and osteosarcoma. 18–20 Consistent with this study, the levels of TUG1 in bladder cancer tissues were significantly higher than those in paired nontumor tissues. These data suggested that TUG1 may exhibit vital roles in bladder cancer development and ... WebThe lncRNA taurine-upregulated gene 1 (TUG1) directly binds to polycomb repressive complex 2 (PRC2) or PRC1 represses gene expression, and has been reported to participate in oncogenic processes. 11,12 TUG1 acts as a key regulator of drug resistance by sponging miRNAs and involved in the control of some cancer-related genes. 13–15 WebOct 17, 2016 · Like most other lncRNAs, the functional role of TUG1 has been poorly understood. TUG1 expression is increased in most cancer types, and knockdown of TUG1 in cultured cancer cells has been shown to suppress cell proliferation, invasion, and colony formation ( 15 ). hay and straw taste of home