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Tug1 lncrna

WebJun 1, 2024 · Long noncoding RNA (lncRNA) is a type of non-coding RNA that is at least 200 nucleotides in length and does not encode any protein (Zhang et al. 2024 ). In recent years, lncRNA has been found to have the function of trapping microRNA (miRNA) and regulating gene functions by reducing the expression level of some miRNAs (Guo et al. … WebThe lncRNA taurine-upregulated gene 1 (TUG1) directly binds to polycomb repressive complex 2 (PRC2) or PRC1 represses gene expression, and has been reported to …

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WebJan 29, 2024 · LncRNA TUG1 reduces inflammation and enhances insulin sensitivity in white adipose tissue by regulating miR-204/SIRT1 axis in obesity mice. LncRNA TUG1 competitively binds to miR-340 to accelerate myocardial ischemia-reperfusion injury. The Tug1 lncRNA locus is essential for male fertility. WebThe lncRNA TUG1, short for Taurine upregulated gene 1, was originally reported to be upregulated in response to taurine treatment of developing mouse retinal cells and has been frequently described as an oncogene in various human cancers. 34–36 UCA1 (urothelial carcinoma associated 1) was initially identified in human bladder carcinoma and ... bothy kits uk https://greenswithenvy.net

The lncRNA TUG1 promotes epithelial ovarian cancer cell …

WebPrevious studies indicated lncRNA TUG1 was upregulated in bladder cancer, gastric cancer, and osteosarcoma. 18–20 Consistent with this study, the levels of TUG1 in bladder cancer tissues were significantly higher than those in paired nontumor tissues. These data suggested that TUG1 may exhibit vital roles in bladder cancer development and ... WebThe lncRNA taurine-upregulated gene 1 (TUG1) directly binds to polycomb repressive complex 2 (PRC2) or PRC1 represses gene expression, and has been reported to participate in oncogenic processes. 11,12 TUG1 acts as a key regulator of drug resistance by sponging miRNAs and involved in the control of some cancer-related genes. 13–15 WebOct 17, 2016 · Like most other lncRNAs, the functional role of TUG1 has been poorly understood. TUG1 expression is increased in most cancer types, and knockdown of TUG1 in cultured cancer cells has been shown to suppress cell proliferation, invasion, and colony formation ( 15 ). hay and straw taste of home

Effects of TUg1 knockdown and overexpression on cell …

Category:Interactions Between lncRNA TUG1 and miR-9-5p Modulate the …

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Tug1 lncrna

lncRNA TUG1 as a ceRNA promotes PM exposure …

Web43791 Devin Shafron Drive, Building D, Ashburn, VA 20147. Strategically located on 98 acres of land in the Dulles technology corridor of Northern Virginia, the Ashburn Campus … WebSep 7, 2024 · The Tug1 lncRNA locus is highly conserved and ubiquitously expressed. a Tug1 mouse genomic locus (shown inverted). UCSC Genome Browser tracks for RNA …

Tug1 lncrna

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WebLncRNA TUG1 promotes the ASMCs proliferation and migration, and reduces apoptosis In the ASMCs cells isolated from the asthma rats, we had found that TUG1 was increased. Thus, in order to discover the roles of TUG1 for the ASMCs, silencing and overexpression of TUG1 was constructed using the siRNA and plasmid transfection ( Figure 2A ). WebMar 14, 2024 · LncRNAs are non-coding RNAs with a transcript length > 200 nucleotides. They are transcribed by RNA polymerase II, capped, spliced, and polyadenylated. They are expressed in a tissue- and...

WebJul 18, 2024 · lncRNA TUG1 expression is increased in human skeletal muscle in response to a single bout of aerobic exercise. Gene expression of A TUG1, B PPARGC1A and C TFAM measured by RT-qPCR from muscle ( vastus lateralis) biopsy samples before (Pre Ex), immediately (Post 0 h) and 3 h after (Post 3 h) a 60-min bout of cycling exercise at … WebAug 8, 2024 · Next, we identified that lncRNA taurine upregulated gene 1 (TUG1)acted as a competing endogenous RNA for microRNA-222–3p (miR-222–3p)and subsequently …

WebMay 26, 2024 · lncRNA TUG1 regulates cancer invasion and metastasis. Up-regulation of lncRNA TUG1 expression exerts a carcinogenic role by promoting the migration, and invasion of laryngeal cancer cells, and by inhibiting apoptosis (Zhang et al. 2024). lncRNA TUG1 participated in the development of laryngeal carcinoma via inhibiting the activation … WebNov 6, 2024 · Taurine upregulated gene 1 ( TUG1) is a long noncoding RNA (lncRNA) that is downregulated in sepsis. The current study was designed to explore the role of EPCs …

WebAug 2, 2016 · The lncRNA taurine-upregulated gene 1 ( TUG1) is a nonprotein-coding gene located on chromosome 22q12.2 that transcribes to a 6.7-kilobase-long, spliced, and …

bothy malluskWebAug 22, 2024 · LncRNA Tug1 Contributes Post-stroke NLRP3 Inflammasome-Dependent Pyroptosis via miR-145a-5p/Tlr4 Axis Pyroptosis, a type of programmed cell death illuminated by inflammasomes and active caspases, is implicated in … hay and tener expressionsWebAug 15, 2024 · lncRNA TUG1 as a ceRNA promotes PM exposure-induced airway hyper-reactivity With the increased appreciation for the significance of noncoding RNAs … bothy locations ukWebTUG1 lncRNA is involved in various aspects of tumor progression, including cell proliferation, migration, and invasion. Downregulation of TUG1 by therapeutic agents may be valuable for the prevention of EOC; thus, our findings indicate that knockdown of TUG1 is a potential novel therapeutic approach for EOC. bothy linn of deeWebJan 29, 2024 · 7.1 kb long lncRNA taurine-upregulated gene 1 (TUG-1) is located on chromosome 22q12. TUG-1 is aberrantly expressed in cancer and has been involved in the progression of various types of tumors: hepatocellular carcinoma, non-small-cell lung cancer (NSCLC), cancer of the bladder, and cancer of the colon [ 13 – 15 ]. bothy malvernWebFeb 8, 2024 · Various lncRNAs are involved in this process. For instance, TUG1 can inhibit miR-132-3p expression, thereby increasing SOX4 expression. This decreases caspase-3 activity, eventually inhibiting... hayange foot facebookWebTUG1 (taurine upregulated gene 1) is a long non-coding RNA expressed in the retina and in the brain. It was first identified in a screen for genes upregulated by in developing retinal … hay and straw trucks