Uic2 antibody
Web19 Sep 2014 · The UIC2 monoclonal antibody recognizes human Pgp and inhibits its drug transport activity. However, this inhibition is partial, since UIC2 binds only to 10–40% of … Web22 Jan 2013 · Product name PE Anti-P Glycoprotein antibody [UIC2] See all P Glycoprotein primary antibodies Description PE Mouse monoclonal [UIC2] to P Glycoprotein Host …
Uic2 antibody
Did you know?
WebThe mouse monoclonal antibody UIC2 recognizes an extracellular epitope on CD243 (MDR-1), an approximately 170 kDa ABC transporter expressed on hematopoietic stem cells, B, … WebEach lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 5.0 - …
WebBuy mouse monoclonal (UIC2) antibody to CD243 (A281888). Applications: IHC, IP and more. Reactivity: Human and Primate. ️ 100% Guarantee Web19 Sep 2014 · The UIC2 monoclonal antibody recognizes human Pgp and inhibits its drug transport activity. However, this inhibition is partial, since UIC2 binds only to 10-40% of cell surface Pgps, while the rest becomes accessible to this antibody only in the presence of certain substrates or modulators (e.g. cyclosporine A (CsA)).
WebApplications Tested: This UIC2 antibody has been pre-titrated and tested by flow cytometric analysis on multidrug resistant cell lines. This can be used at 5 µL (0.5 µg) per test. A test is defined as the amount (µg) of antibody that will stain a … WebThe drug-resistance phenotype of P-gp can be modulated by the monoclonal antibody UIC2, which specifically recognizes human P-gp in a conformation-dependent manner. Here, the purification, sequence determination and high-resolution structure of the Fab fragment of UIC2 (UIC2/Fab) are reported.
WebEnter the email address you signed up with and we'll email you a reset link.
WebThe effect of HD37 on the function on P-gp pump appears to Previous studies by O’Connor et al. (6) and Liu et al. (7) involve a cytoplasmic pathway because, in contradistinction to demonstrated that an anti-CD19 IT increased the drug sensitiv- UIC2 and verapamil, the anti-CD19 antibody did not effect the ity of MDR lymphoma cells. spectrum account online loginWebThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. Application FC - Quality tested. Recommended … spectrum account security codeWebThe UIC2 monoclonal antibody specifically binds to an extracellular epitope of CD243, which is also known as ATP-binding cassette subfamily B member 1 (ABCB1), Multidrug resistance protein 1 (MDR1), or P-glycoprotein 1. CD243 is a transmembrane glycoprotein that spans the membrane 12 times. spectrum acp phone numberWebIntroduction On January 6, 2024, lecanemab (Leqembi) was granted accelerated approval by the United States Food and Drug Administration (FDA) for the treatment of early Alzheimer disease (AD). 1 The second in its class, lecanemab is preceded by the controversial amyloid beta-directed monoclonal antibody, aducanumab (Aduhelm). Like aducanumab, … spectrum acp program phone numberWebBuy mouse monoclonal (UIC2) antibody to CD243 (A121698). Validated Applications: Flow Cytometry. Reactivity: Human. ️ Low Prices ️ 100% Guarantee spectrum acp program applicationWebAPC Anti-P Glycoprotein antibody [UIC2] See all P Glycoprotein primary antibodies Description APC Mouse monoclonal [UIC2] to P Glycoprotein Host species Mouse Conjugation APC. Ex: 645nm, Em: 660nm Tested … spectrum acting upWebEach lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 5.0 - 10 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application. spectrum acquires time warner cable